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Mycopathologia
08-1999, Volume 147, Issue 2, pp 63-65
The antifungal action of dandruff shampoos
- Amelia C. Bulmer,
- Glenn S. Bulmer
- … show all 2 hide
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Abstract
The disease commonly known as “dandruff” is caused by numerous host factors in conjunction with the normal flora yeast Malassezia furfur (Pityrosporumovale). Indeed, clinical studies have shown that administration of antifungal agents correlates with an improved clinical condition. Almost all commercially available hair shampoos publicize that they contain some form of antifungal agent(s). However, few studies have been published in which antifungal activity of commercially available hair shampoos have been contrasted experimentally. In this study six commercially available shampoos (in the Philippines) were assessed for antifungal activity against a human (dandruff) isolate of M. furfur: (a) Head & Shoulders (Proctor & Gamble); (b) Gard Violet (Colgate-Palmolive); (c) Nizoral 1% (Janssen); (d)Nizoral 2% (Janssen); (e) Pantene Blue (Proctor & Gamble); and (f) Selsun Blue (Abbott). The results demonstrated that all six of the assayed hair shampoos have some antifungal effect on the test yeast. However, there was consider variation in potency of antifungal activity. Nizoral 1% and Nizoral 2% shampoo preparations were the most effective. The 1% Nizoral shampoo was consistently 10X better at killing yeast cells than the next closest rival shampoo. The 2% Nizoral shampoo was 10X better than the Nizoral 1% product and 100 times better than any of the other products assayed. The study demonstrated that shampoos containing a proven antifungal compound were the most effective in controlling the causative yeast.
This revised version was published online in June 2006 with corrections to the Cover Date.
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References (5)
- Kane J, Summerbell RC.Trichophyton, Microsporum, Epidermophyton, and agents of superficial mycoses. In: Murray PR, Barron EJ, Pfaller MA, Tenover FC, Yolken RH, eds. Manual of Clinical Microbiology, 7th edn. American Society for Microbiology Press, Washington, DC, 1999; 1275–1294.
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About this Article
Title
The antifungal action of dandruff shampoos
Journal
Mycopathologia
Volume 147, Issue 2 , pp 63-65
Cover Date
1999-08-01
DOI
10.1023/A:1007132830164
Print ISSN
0301-486X
Online ISSN
1573-0832
Publisher
Kluwer Academic Publishers
Additional Links
- Register for Journal Updates
- Editorial Board
- About This Journal
- Manuscript Submission
Topics
- Medical Microbiology
- Microbial Ecology
- Microbiology
- Plant Sciences
Keywords
- antifungal
- dandruff
- ketoconazole
- Malassezia furfur
- Nizoral
- Philippines
- Pityrosporum ovale
Industry Sectors
- Biotechnology
- Consumer Packaged Goods
- Health & Hospitals
- Pharma
Authors
- Amelia C. Bulmer (1)
- Glenn S. Bulmer (1)
Author Affiliations
- 1. J.F. Cotton Hospital, Dermatology Section, and the, University of Santo Tomas School of Medicine, Medical Mycology Section, Manila, Philippines
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